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Regarding brain tumors AXL has been implicated in gliomagene
2024-01-23
Regarding ampicillin sodium tumors, AXL has been implicated in gliomagenesis and chemoresistance [39]. Previous investigations found that AXL is constitutively phosphorylated in many glioma cell lines, murine xenograft tumors and primary patient tumor samples [40]. Immunohistochemical analysis of A
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br Involvement of LPA receptors in cancer LPA
2024-01-23
Involvement of LPA receptors in cancer LPA׳s effects are mediated by at least six different G protein-coupled receptors (LPA1–6). Human gastric and ovarian cancers overexpress the mRNA encoding LPA1 and LPA2 compared to healthy tissues [6], [11], [12]. Papillary and follicular thyroid cancers exh
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br Author contributions br Conflicts of
2024-01-23
Author contributions Conflicts of interest The authors declare no competing financial interests. Acknowledgement This work was supported by grants from the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich/Transregio 166–Project C1 and grant CA 1014/1-1 to D.C.) and the IZKF Würzbur
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Introduction Enzymatic browning degrades quality safety
2024-01-23
Introduction Enzymatic browning degrades quality, safety, and nutritional values of various fruits or vegetable products. For example, the color of apple or potato is generally yellowish, representing freshness. However, they are extremely susceptible to enzymatic browning because of abundant polyp
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Growth inhibition assays are the most commonly used to
2024-01-23
Growth-inhibition assays are the most commonly used to identify antifungal small molecules. However, they have several facts that limit their use since many pathogenic fungi grow as filaments making difficult a correlation between growth and OD (optical density). They are not useful for identifying
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Given that the FST protocol for mice does not
2024-01-23
Given that the FST protocol for mice does not engage the exposure to a previous stressful session, posits that Agtr1a levels could be kept higher by basal glutamatergic transmission rather than by stressful stimuli as postulated before. To address this possibility, we used the EMBL-EBI Expression At
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The primary structure of the A peptide can
2024-01-23
The primary structure of the Aβ peptide can be divided into four regions based on hydrophobicity. The N-terminal residues 1–16 comprise the first hydrophilic region, which also contains the metal binding site. More specifically, side chain carboxylate of D1 and the side chain nitrogens of H6, H13 an
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SB 204070 br Acknowledgments and Disclosures br Introduction
2024-01-23
Acknowledgments and Disclosures Introduction Over the last decade, the most visible strategy for the treatment of Alzheimer's disease (AD) has been amyloid β peptide (Aβ) immunotherapy (reviewed in [1]). Although the first efforts with Aβ immunotherapy failed to complete clinical trials [1], A
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br Conclusions br Material and methods br Conflicts of inter
2024-01-23
Conclusions Material and methods Conflicts of interest Acknowledgements Introduction Currently more than 30 human proteins are implicated in a range of degenerative disorders owing to their misfolding and misassembly into various aggregate structures and leading to at least 20 serious
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To determine the post translation modifications in chicken a
2024-01-22
To determine the post-translation modifications in chicken adiponectin, we isolated adiponectin from chicken adipose tissue by immunoprecipitation. Chicken adiponectin was then subjected to tryptic digestion and UPLC/MS/MS. The collagenous domain of chicken adiponectin was found to possess certain p
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Ultraviolet UV spectroscopy is commonly
2024-01-22
Ultraviolet (UV) spectroscopy is commonly used for screening potential ADA inhibitors [15]. In the UV method, the ADA reaction is calculated by measuring the decrease in absorbance of the substrate at 265 nm or increase in absorbance of the product at 248 nm. However, AD and inosine share a very clo
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As also found by Stolarski et al inclusion of N
2024-01-22
As also found by Stolarski et al. [14], inclusion of N2O in the model is successful in reducing the effect of dynamics [13] in the lower stratosphere in the Northern Hemisphere (30–60°N in our case). The inclusion of N2O also decreased the error bars on the trend values, but the trend values still c
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Although CP has been an important research subject in
2024-01-22
Although CP has been an important research subject in the field of antigen processing and presentation, the mechanisms of presentation of intracellular hiv protease by MHC II received considerably less attention. Interestingly, pioneering work by the Münz laboratory has pointed to an involvement of
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br Materials and methods br
2024-01-22
Materials and methods Results Discussion Numerous studies showed that Na+-K+-ATPase activity and membrane KPT-276 were decreased in cardiac tissue subjected to IR (Belliard et al., 2013; Lee et al., 2013). In return, treatment that alleviated the progress of IR-related myocardial injury is
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Cimetidine mg br Results br Discussion br
2024-01-22
Results Discussion Conclusions In summary, this study provides novel report of pericardial adipose aromatase expression – in both human and rodent. We show that aromatase expression is remarkably upregulated with aging (Fig. 1C), and that total aromatase Cimetidine mg conversion capacity is
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